TNFalpha genotype influences development of IgA-ASCA antibodies in Crohn's disease patients with CARD15 wild type

A typical feature of Crohn's disease (CD) patients is the development of antibodies against self- (PAB) or exogenous (ASCA) antigens, a process in which mucosal cytokine expression pattern might be involved. On the other hand, mutations in CARD15, a genetic risk factor for CD, alter cytokine pr...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 3 vom: 30. Dez., Seite 305-13
1. Verfasser: Castro-Santos, Patricia (VerfasserIn)
Weitere Verfasser: Mozo, Lourdes, Gutiérrez, Carmen, Suárez, Ana
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Antibodies, Fungal Biomarkers Immunoglobulin A NOD2 protein, human Nod2 Signaling Adaptor Protein Tumor Necrosis Factor-alpha Interleukin-10 130068-27-8