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231223s2006 xx ||||| 00| ||eng c |
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|c DE-627
|e rakwb
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|a eng
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1 |
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|a Dilly, Suzanne J
|e verfasserin
|4 aut
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| 245 |
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|a Novel tertiary amine oxide surfaces that resist nonspecific protein adsorption
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|c 2006
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 06.09.2007
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|a Date Revised 01.12.2018
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|a published: Print
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|a Citation Status MEDLINE
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|a Novel surfaces derivatized with tertiary amine oxides have been prepared and tested for their ability to resist nonspecific protein adsorption. The oxidation of tertiary amines supported on triazine units was carried out using mCPBA to give a format allowing conjugation of biologically active ligands alongside them. Adsorption to these surfaces was tested and compared to adsorption to a set of commercial and custom oligo-/poly(ethylene glycol) (OEG/PEG) supports by challenging them with a protein display library presented on bacteriophage lambda. The new class of amine oxide surfaces is found to compare favorably with the performance of the OEG/PEG supports in the prevention of nonspecific binding
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Amines
|2 NLM
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|a Ligands
|2 NLM
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|a Oxides
|2 NLM
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|a Proteins
|2 NLM
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|a Triazines
|2 NLM
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|a Polyethylene Glycols
|2 NLM
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| 650 |
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|a 3WJQ0SDW1A
|2 NLM
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| 700 |
1 |
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|a Beecham, Matthew P
|e verfasserin
|4 aut
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1 |
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|a Brown, Steven P
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Griffin, John M
|e verfasserin
|4 aut
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1 |
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|a Clark, Andrew J
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Griffin, Craig D
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Marshall, Jacqueline
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Napier, Richard M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Taylor, Paul C
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Marsh, Andrew
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 22(2006), 19 vom: 12. Sept., Seite 8144-50
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:22
|g year:2006
|g number:19
|g day:12
|g month:09
|g pages:8144-50
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