Redox-active biomolecular architectures and self-assembled monolayers based on a cyclodecapeptide regioselectively addressable functional template
A nanometer scale redox active biomolecular architecture has been successfully synthesized through an efficient chemoselective oxime based coupling between ferrocenyl groups and a regioselectively addressable cyclodecapeptide. This molecular tool exhibits electronic, structural, and chemical propert...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1991. - 22(2006), 19 vom: 12. Sept., Seite 8134-43 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2006
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Ferrous Compounds Metallocenes Oligopeptides Peptides, Cyclic ferrocene U96PKG90JQ |
| Zusammenfassung: | A nanometer scale redox active biomolecular architecture has been successfully synthesized through an efficient chemoselective oxime based coupling between ferrocenyl groups and a regioselectively addressable cyclodecapeptide. This molecular tool exhibits electronic, structural, and chemical properties driven by the biomimetic recognition activity of the polypeptide skeleton associated to the well-defined electrochemical activity of metallocenyl probes. Biomolecular materials obtained by confinement of the redox cyclopeptide in self-assembled monolayers on gold surfaces shows efficient through-bond electron transfer from the ferrocenes to the electrode surface via the peptidic backbone, as well as markedly improved sensing properties toward anionic species in organic electrolyte, as compared to those observed in homogeneous solution |
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| Beschreibung: | Date Completed 06.09.2007 Date Revised 16.11.2017 published: Print Citation Status MEDLINE |
| ISSN: | 0743-7463 |