Function and recruitment of mucosal regulatory T cells in human chronic Helicobacter pylori infection and gastric adenocarcinoma

Function and recruitment of mucosal regulatory T cells in human chronic Helicobacter pylori infection and gastric adenocarcinoma

CD4(+)CD25(high) FOXP3-expressing regulatory T cells (Treg) can suppress immune responses to infections and tumors, thereby promoting microbial persistence and tumor progression. However, little is known about the phenotype and function of human mucosal Treg. Therefore, we analyzed the suppressive a...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 3 vom: 01. Dez., Seite 358-68
1. Verfasser: Enarsson, Karin (VerfasserIn)
Weitere Verfasser: Lundgren, Anna, Kindlund, Bert, Hermansson, Mikael, Roncador, Giovanna, Banham, Alison H, Lundin, B Samuel, Quiding-Järbrink, Marianne
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't CCL17 protein, human CCL22 protein, human CCR4 protein, human Chemokine CCL17 Chemokine CCL22 Chemokines, CC FOXP3 protein, human Forkhead Transcription Factors mehr... Interleukin-2 Receptor alpha Subunit Receptors, CCR4 Receptors, Chemokine