IL-10 gene modified dendritic cells induced antigen-specific tolerance in experimental autoimmune myocarditis

IL-10 gene modified dendritic cells induced antigen-specific tolerance in experimental autoimmune myocarditis

Experimental autoimmune myocarditis (EAM) in rats is a T-cell-mediated disorder, and the involvement of Th1/Th2 unbalance has been demonstrated. The induction of antigen-specific tolerance is critical for the treatment of EAM and maintenance of immune tolerance. IL-10 is a pleiotrophic immunomodulat...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 1 vom: 15. Okt., Seite 63-73
1. Verfasser: Yang, Shusen (VerfasserIn)
Weitere Verfasser: Li, Weimin, Liu, Wei, Gao, Cheng, Zhou, Baoguo, Li, Shaojun, Li, Yue, Kong, Yihui
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Autoantigens Epitopes Interleukin-10 130068-27-8