The transferrin receptor part I : Biology and targeting with cytotoxic antibodies for the treatment of cancer

The transferrin receptor (TfR) is a cell membrane-associated glycoprotein involved in the cellular uptake of iron and in the regulation of cell growth. Iron uptake occurs via the internalization of iron-loaded transferrin (Tf) mediated by the interaction with the TfR. In addition, the TfR may also c...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 2 vom: 15. Nov., Seite 144-58
1. Verfasser:	Daniels, Tracy R (VerfasserIn)
Weitere Verfasser:	Delgado, Tracie, Rodriguez, Jose A, Helguera, Gustavo, Penichet, Manuel L
Format:	Aufsatz
Sprache:	English
Veröffentlicht:	2006
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Antibodies, Monoclonal Receptors, Transferrin TFR2 protein, human Transferrin Iron E1UOL152H7