Identification of two Melan-A CD4+ T cell epitopes presented by frequently expressed MHC class II alleles

Identification of two Melan-A CD4+ T cell epitopes presented by frequently expressed MHC class II alleles

Because of its expression pattern restricted to cells of the melanocytic lineage and to melanoma cells, Melan-A is an important target of immunotherapeutic approaches for the treatment of melanoma. Identification of Melan-A derived sequences recognized by specific T cells is therefore of great inter...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 1 vom: 01. Okt., Seite 54-62
1. Verfasser: Godefroy, Emmanuelle (VerfasserIn)
Weitere Verfasser: Scotto, Luigi, Souleimanian, Naira E, Ritter, Gerd, Old, Lloyd J, Jotereau, Francine, Valmori, Danila, Ayyoub, Maha
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, Neoplasm Epitopes, T-Lymphocyte HLA-DR Antigens HLA-DR Serological Subtypes HLA-DR11 antigen HLA-DR5 Antigen Histocompatibility Antigens Class II MART-1 Antigen mehr... MLANA protein, human Neoplasm Proteins