Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis

Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis

Macrophage migration inhibitory factor (MIF) is a cytokine that has potent anti-steroid effects and might be implicated in the pathogenesis of Ulecrative colitis (UC). We defined the functional role of MIF in the glucocorticoid (GC)-resistant inflammatory response in UC. Twenty-four colonic samples...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 3 vom: 19. Sept., Seite 335-41
1. Verfasser: Ishiguro, Yoh (VerfasserIn)
Weitere Verfasser: Ohkawara, Tatsuya, Sakuraba, Hirotake, Yamagata, Kazufumi, Hiraga, Hiroto, Yamaguchi, Satoko, Fukuda, Shinsaku, Munakata, Akihiro, Nakane, Akio, Nishihira, Jun
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Glucocorticoids Imidazoles Interleukin-8 Macrophage Migration-Inhibitory Factors Protein Kinase Inhibitors Pyridines p38 Mitogen-Activated Protein Kinases EC 2.7.11.24 mehr... SB 203580 OU13V1EYWQ