Drying of DNA droplets
The evaporation kinetics of droplets containing DNA was studied, as a function of DNA concentration. Drops containing very low DNA concentrations dried by maintaining a constant base, whereas those with high concentration dried with a constant contact angle. To understand this phenomenon, the distri...
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1999. - 22(2006), 14 vom: 04. Juli, Seite 6308-12 |
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1. Verfasser: | |
Weitere Verfasser: | , , , , , , , |
Format: | Aufsatz |
Sprache: | English |
Veröffentlicht: |
2006
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Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
Schlagworte: | Journal Article Research Support, U.S. Gov't, Non-P.H.S. DNA, Viral |
Zusammenfassung: | The evaporation kinetics of droplets containing DNA was studied, as a function of DNA concentration. Drops containing very low DNA concentrations dried by maintaining a constant base, whereas those with high concentration dried with a constant contact angle. To understand this phenomenon, the distribution of the DNA inside the droplet was measured using confocal microscopy. The results indicated that the DNA was condensed mostly on the surface of the droplets. In the case of high concentration droplets, it formed a shell, whereas isolated islands were found for droplets of low DNA concentrations. Rheologic results indicate the formation of a hydro gel in the low concentration drops, whereas phase separation between the self-assembled DNA structures and the water phase occurred at higher concentration |
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Beschreibung: | Date Completed 03.08.2007 Date Revised 27.06.2006 published: Print Citation Status MEDLINE |
ISSN: | 1520-5827 |