CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells

CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells

We previously reported that 4C8 monoclonal antibody (mAb) provides a costimulatory signal to human CD4+ T cells and consequently induces regulatory T (Treg) cells, which are hypo-responsive and suppress the polyclonal response of bystander CD4+ cells in a contact-dependent manner. In this study, we...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 3 vom: 04. Sept., Seite 247-59
1. Verfasser: Watanabe, Tomoko (VerfasserIn)
Weitere Verfasser: Masuyama, Jun-ichi, Sohma, Yoshiaki, Inazawa, Hiroko, Horie, Kaori, Kojima, Kumiko, Uemura, Yasunori, Aoki, Yumi, Kaga, Shuji, Minota, Seiji, Tanaka, Toshiyuki, Yamaguchi, Yasunori, Kobayashi, Tetsuto, Serizawa, Isao
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article 4C8 antigen, human Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Antibodies, Neoplasm Antigens, CD Antigens, Neoplasm CD52 Antigen CD52 protein, human Enterotoxins mehr... Epitopes, T-Lymphocyte FOXP3 protein, human Forkhead Transcription Factors Glycoproteins Interleukin-2 enterotoxin B, staphylococcal 39424-53-8 Alemtuzumab 3A189DH42V