Regulation of T:B cell interactions by the inducible costimulator molecule does ICOS "induce" disease?

Regulation of T:B cell interactions by the inducible costimulator molecule : does ICOS "induce" disease?

The Inducible Costimulator molecule (ICOS), a member of the CD28 family of costimulatory molecules, was identified in 1999 as a molecule expressed primarily on activated human T cells. Induced upon activation, ICOS appears to be an ideal target for modifying T-cell-mediated immune responses. ICOS wa...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 1 vom: 24. Okt., Seite 13-8
1. Verfasser: Shilling, Rebecca A (VerfasserIn)
Weitere Verfasser: Bandukwala, Hozefa S, Sperling, Anne I
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Antigens, Differentiation, T-Lymphocyte ICOS protein, human Inducible T-Cell Co-Stimulator Protein