Use of acute physiology and chronic health evaluation III in evaluating prognosis of chronic obstructive pulmonary disease in elderly patients on mechanical ventilation

OBJECTIVE: To investigate the feasibility of estimating risk of prognosis and hospital mortality in elderly patients (> or =60 years old) with chronic obstructive pulmonary disease (COPD) under the treatment of mechanical ventilation by using acute physiology and chronic health evaluation III (AP...

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Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 18(2006), 6 vom: 20. Juni, Seite 373-5
1. Verfasser: Long, Wei (VerfasserIn)
Weitere Verfasser: Xie, Miao-rong
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article
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245 1 0 |a Use of acute physiology and chronic health evaluation III in evaluating prognosis of chronic obstructive pulmonary disease in elderly patients on mechanical ventilation 
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500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To investigate the feasibility of estimating risk of prognosis and hospital mortality in elderly patients (> or =60 years old) with chronic obstructive pulmonary disease (COPD) under the treatment of mechanical ventilation by using acute physiology and chronic health evaluation III (APACHE III) 
520 |a METHODS: Fifty elderly patients with COPD treated with mechanical ventilation were analyzed retrospectively. A risk estimation equation for hospital mortality was first developed by using APACHE III in evaluating 40 randomly-selected patients before mechanical ventilation. Changes in APACHE III on the 1 st, 3 rd and 7 th day for each patient after intubation were recorded and analyzed 
520 |a RESULTS: The risk estimate equation for hospital mortality was developed as p=Apa(gamma)/(D(gamma)(50)+Apa(gamma)), D(50)=73.4, gamma=8 with 80% prediction accuracy. A statistical significant cutoff was developed by dynamically recording acute physiology scores after intubation, and a decrease of 32.8% or more (compared with APACHE III before intubation) of APACHE III on the 3 rd day predicted survival of the patient 
520 |a CONCLUSION: APACHE III score and its dynamic change could be an ideal tool to predict risk for hospital mortality in elderly patients with COPD on mechanical ventilation 
650 4 |a English Abstract 
650 4 |a Journal Article 
700 1 |a Xie, Miao-rong  |e verfasserin  |4 aut 
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