Cytochemical detection of calcium in a case of calcinosis circumscripta in a dog

A 9-month-old intact female Serra-da-Estrela dog (giant Portuguese breed) was presented with a 2-month history of lingual lesions. Two hard, nodular, nonpainful lesions were observed on the lateral border of the tongue. Fine-needle aspiration yielded a chalky white material. Hemacolor-stained smears...

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Veröffentlicht in:Veterinary clinical pathology. - 1975. - 35(2006), 2 vom: 16. Juni, Seite 239-42
1. Verfasser: Marcos, R (VerfasserIn)
Weitere Verfasser: Santos, M, Oliveira, J, Vieira, M J, Vieira, A L, Rocha, E
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Case Reports Journal Article Calcium SY7Q814VUP
Beschreibung
Zusammenfassung:A 9-month-old intact female Serra-da-Estrela dog (giant Portuguese breed) was presented with a 2-month history of lingual lesions. Two hard, nodular, nonpainful lesions were observed on the lateral border of the tongue. Fine-needle aspiration yielded a chalky white material. Hemacolor-stained smears showed an amorphous granular basophilic background with crystal-like structures and granulomatous inflammation consisting of foamy macrophages and giant cells. Cytochemical staining with von Kossa and Alizarin red S confirmed the calcareous nature of the material. The cytologic diagnosis was lingual calcinosis circumscripta; this was later confirmed by histopathologic examination. To our knowledge, this case is the first to document the use of von Kossa and Alizarin red S on cytologic smears to obtain a definitive diagnosis of lingual calcinosis circumscripta
Beschreibung:Date Completed 08.08.2006
Date Revised 10.11.2019
published: Print
Citation Status MEDLINE
ISSN:0275-6382