Long-lived effector/central memory T-cell responses to severe acute respiratory syndrome coronavirus (SARS-CoV) S antigen in recovered SARS patients

The role of cell-mediated immunity in human SARS-CoV infection is still not well understood. In this study, we found that memory T-cell responses against the spike (S) protein were persistent for more than 1 year after SARS-CoV infection by detecting the production of IFN-gamma using ELISA and ELISp...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 2 vom: 15. Aug., Seite 171-8
1. Verfasser: Yang, Li-Tao (VerfasserIn)
Weitere Verfasser: Peng, Hui, Zhu, Zhao-Ling, Li, Gang, Huang, Zi-Tong, Zhao, Zhi-Xin, Koup, Richard A, Bailer, Robert T, Wu, Chang-You
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, Viral Antiviral Agents Interleukin-2 Membrane Glycoproteins Peptides Spike Glycoprotein, Coronavirus Viral Envelope Proteins spike glycoprotein, SARS-CoV mehr... spike protein, mouse hepatitis virus Interferon-gamma 82115-62-6