Leptin enhances in vitro secretion of IgG antiplatelet antibodies by splenocytes and peripheral blood mononuclear cells from patients with chronic idiopathic thrombocytopenic purpura

Leptin enhances in vitro secretion of IgG antiplatelet antibodies by splenocytes and peripheral blood mononuclear cells from patients with chronic idiopathic thrombocytopenic purpura

Chronic idiopathic thrombocytopenic purpura (ITP) is an organ-specific autoimmune disease characterized by the production of antibodies against antigens on the membranes of platelets, resulting in enhanced destruction of the platelets by macrophages. Leptin, a cytokine-like hormone, plays a role in...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 2 vom: 01. Aug., Seite 205-11
1. Verfasser: Ren, He (VerfasserIn)
Weitere Verfasser: Zhao, Hui, Wang, Tingting, Yang, Yanhui, Han, Zhibo, Liu, Bin, Wu, Zida, Tao, Jie, Zhou, Bin, Zhang, Lei, Yang, Renchi, Han, Zhong Chao
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Autoantibodies Immunoglobulin G Leptin