Effect of an oscillating magnetic field on the release properties of magnetic collagen gels

The paper describes the effect of an oscillating magnetic field (OMF) on the morphology and release properties of collagen gels containing magnetic nanoparticles and microparticles and fluorescent drug analogues. Collagen gels were prepared through fibrillogenesis of collagen in the presence of iron...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 22(2006), 13 vom: 20. Juni, Seite 5894-9
1. Verfasser: De Paoli, Vania M (VerfasserIn)
Weitere Verfasser: De Paoli Lacerda, Silvia H, Spinu, Leonard, Ingber, Bruce, Rosenzweig, Zeev, Rosenzweig, Nitsa
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Dextrans Drug Carriers Ferric Compounds Fluorescent Dyes Fluoro-Ruby Gels Rhodamines mehr... ferric oxide 1K09F3G675 Collagen 9007-34-5
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245 1 0 |a Effect of an oscillating magnetic field on the release properties of magnetic collagen gels 
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520 |a The paper describes the effect of an oscillating magnetic field (OMF) on the morphology and release properties of collagen gels containing magnetic nanoparticles and microparticles and fluorescent drug analogues. Collagen gels were prepared through fibrillogenesis of collagen in the presence of iron oxide magnetic particles averaging 10 nm or 3 mum in diameter and rhodamine-labeled dextran (Dex-R) of molecular weights between 3000-70 000 g/mol. Dextran molecules effectively simulate protein-based drugs, since they have similar molecular weights and dimensions. The paper discusses the effect of an OMF on the release properties of the gels and proposes an empirical model to predict the release rate. It also demonstrates the self-repair capability of collagen gels following the structural damage caused by an OMF 
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650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
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700 1 |a De Paoli Lacerda, Silvia H  |e verfasserin  |4 aut 
700 1 |a Spinu, Leonard  |e verfasserin  |4 aut 
700 1 |a Ingber, Bruce  |e verfasserin  |4 aut 
700 1 |a Rosenzweig, Zeev  |e verfasserin  |4 aut 
700 1 |a Rosenzweig, Nitsa  |e verfasserin  |4 aut 
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