Exploring the interaction of ruthenium(II) polypyridyl complexes with DNA using single-molecule techniques

Exploring the interaction of ruthenium(II) polypyridyl complexes with DNA using single-molecule techniques

Here we explore DNA binding by a family of ruthenium(II) polypyridyl complexes using an atomic force microscope (AFM) and optical tweezers. We demonstrate using AFM that Ru(bpy)2dppz2+ intercalates into DNA (K(b) = 1.5 x 10(5) M(-1)), as does its close relative Ru(bpy)2dppx2+ (K(b) = 1.5 x 10(5) M(-...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1991. - 22(2006), 10 vom: 09. Mai, Seite 4699-709
1. Verfasser: Mihailovic, Aleksandra (VerfasserIn)
Weitere Verfasser: Vladescu, Ioana, McCauley, Micah, Ly, Elaine, Williams, Mark C, Spain, Eileen M, Nuñez, Megan E
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Organometallic Compounds Pyridines Ruthenium 7UI0TKC3U5 DNA 9007-49-2