Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse

Recently, glycogen synthase kinase-3 (GSK-3) has being identified as an ubiquitous serine-threonine protein kinase that participates in a multitude of cellular processes and plays an important role in the pathophysiology of a number of diseases. The aim of this study was to investigate the effects o...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 1 vom: 18. Juli, Seite 57-67
1. Verfasser: Cuzzocrea, Salvatore (VerfasserIn)
Weitere Verfasser: Mazzon, Emanuela, Di Paola, Rosanna, Muià, Carmelo, Crisafulli, Concetta, Dugo, Laura, Collin, Marika, Britti, Domenico, Caputi, Achille P, Thiemermann, Christoph
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Retracted Publication 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione Chemokine CCL3 Chemokine CCL4 Chemokine CXCL2 Collagen Type II Interleukin-6 Macrophage Inflammatory Proteins mehr... Monokines Protein Kinase Inhibitors Thiadiazoles Tumor Necrosis Factor-alpha 3-nitrotyrosine 3604-79-3 Tyrosine 42HK56048U Nitric Oxide Synthase Type II EC 1.14.13.39 Cyclooxygenase 2 EC 1.14.99.1 Poly(ADP-ribose) Polymerases EC 2.4.2.30 Glycogen Synthase Kinase 3 beta EC 2.7.11.1 Gsk3b protein, mouse Glycogen Synthase Kinase 3 EC 2.7.11.26