Determination of the DeltapKa between the active site cysteines of thioredoxin and DsbA

Thioredoxin superfamily members share a considerable degree of structural similarity, with a conserved CX(i)X(j)C motif at the active site, where C stand for two cysteines that alternate between a reduced thiol and oxidized disulfide states, and X(i)and X(j) are two amino acids different in each fam...

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Veröffentlicht in:Journal of computational chemistry. - 1984. - 27(2006), 8 vom: 05. Juni, Seite 966-75
1. Verfasser: Carvalho, Alexandra T P (VerfasserIn)
Weitere Verfasser: Fernandes, P A, Ramos, Maria J
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Journal of computational chemistry
Schlagworte:Comparative Study Journal Article Research Support, Non-U.S. Gov't Sulfhydryl Compounds Thioredoxins 52500-60-4 Protein Disulfide-Isomerases EC 5.3.4.1 Cysteine K848JZ4886