CD4+CD25+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence
We hypothesized that advanced age and medical conditions had an impact on the accumulation of CD4+CD25+ T regulatory cells (Treg), which in turn could deteriorate cytotoxic activity of CD8+ T and NK cells. Volunteers were divided according to the Senieur Protocol into healthy young and elderly and n...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 3 vom: 01. Juni, Seite 307-16 |
|---|---|
| 1. Verfasser: | |
| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2006
|
| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't CD4 Antigens Interleukin-2 Membrane Glycoproteins Pore Forming Cytotoxic Proteins Receptors, Interleukin-2 Perforin 126465-35-8 Interferon-gamma mehr... |