Induction of Tc1 response and enhanced cytotoxic T lymphocyte activity in mice by dendritic cells transduced with adenovirus expressing HBsAg

Induction of Tc1 response and enhanced cytotoxic T lymphocyte activity in mice by dendritic cells transduced with adenovirus expressing HBsAg

We evaluated the potential of dendritic cells (DCs) engineered to express antigen of hepatitis B virus (HBV) in priming Th/Tc and HBV-specific CTL responses in mice. Recombinant adenovirus expressing hepatitis B surface antigen (HBsAg) (Ad-S) was constructed, and bone marrow-derived DCs were transdu...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 3 vom: 01. Juni, Seite 280-90
1. Verfasser: Huang, Yin (VerfasserIn)
Weitere Verfasser: Chen, Zhi, Jia, Hongyu, Wu, Wei, Zhong, Shigen, Zhou, Cheng
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't DNA, Viral Hepatitis B Surface Antigens Vaccines, DNA Interleukin-4 207137-56-2 Interferon-gamma 82115-62-6