Changes in serum leptin levels in patients with surgically induced stress responses

OBJECTIVE: To explore the effect of operative trauma induced stress responses on serum leptin levels

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 18(2006), 3 vom: 09. März, Seite 172-5
1. Verfasser: Yan, Guang-tao (VerfasserIn)
Weitere Verfasser: Hao, Xiu-hua, Xue, Hui, Lin, Ji, Zhang, Kai, Wang, Lu-huan
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't Leptin Granulocyte Colony-Stimulating Factor 143011-72-7 Adrenocorticotropic Hormone 9002-60-2 C-Reactive Protein 9007-41-4
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100 1 |a Yan, Guang-tao  |e verfasserin  |4 aut 
245 1 0 |a Changes in serum leptin levels in patients with surgically induced stress responses 
264 1 |c 2006 
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500 |a Date Completed 05.01.2010 
500 |a Date Revised 09.03.2006 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To explore the effect of operative trauma induced stress responses on serum leptin levels 
520 |a METHODS: Serum samples of patients who had undergone resection of hepatic tumors or cholecystectomy were collected, and highly sensitive radioimmunoassay and enzyme-linked immunoadsorbent assay (ELISA) were used to determine serum levels of leptin, granulocyte-clone stimulating factor (G-CSF), C-reactive protein (CRP) and adrenocorticotropin hormone (ACTH) in the blood of these patients 
520 |a RESULTS: Compared with self-control before operation, serum leptin levels decreased slightly right after an abdominal operation (T0), it reached the highest level 1 day after operation (T1), and began to decrease from 2 days (T2) to 4 days after operation (T4), but the level was still higher than that before operation. Serum leptin levels of patients undergoing laparoscopic operation showed no significant difference when compared with that of laparotomy patients. G-SF levels decreased significantly after operation in both groups, and didn't recover to the levels before operation from T1 to T4. CRP levels slightly decreased in both groups at T0, but increased significantly higher than the levels before operation from T1 to T4. ACTH levels of decreased significantly in laparotomy patients from T0 to T1, and began to recover on T2, while that of laparoscopic operation patients showed no significant difference before and after operation 
520 |a CONCLUSION: Serum leptin levels of patients increase significantly and constantly subsequent to operative trauma induced stress responses, but this change has no correlation with that of CRP, G-SF and ACTH 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Leptin  |2 NLM 
650 7 |a Granulocyte Colony-Stimulating Factor  |2 NLM 
650 7 |a 143011-72-7  |2 NLM 
650 7 |a Adrenocorticotropic Hormone  |2 NLM 
650 7 |a 9002-60-2  |2 NLM 
650 7 |a C-Reactive Protein  |2 NLM 
650 7 |a 9007-41-4  |2 NLM 
700 1 |a Hao, Xiu-hua  |e verfasserin  |4 aut 
700 1 |a Xue, Hui  |e verfasserin  |4 aut 
700 1 |a Lin, Ji  |e verfasserin  |4 aut 
700 1 |a Zhang, Kai  |e verfasserin  |4 aut 
700 1 |a Wang, Lu-huan  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue  |d 1998  |g 18(2006), 3 vom: 09. März, Seite 172-5  |w (DE-627)NLM098227793  |x 1003-0603  |7 nnns 
773 1 8 |g volume:18  |g year:2006  |g number:3  |g day:09  |g month:03  |g pages:172-5 
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