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231223s2006 xx ||||| 00| ||chi c |
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|a pubmed25n0537.xml
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|a (DE-627)NLM161153941
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|a (NLM)16524504
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a chi
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100 |
1 |
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|a Gao, Xin-yue
|e verfasserin
|4 aut
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|a Comparison of effects of two kinds of fluid for resuscitation on bacterial translocation and inflammation of small intestine in rats with hemorrhagic shock
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|c 2006
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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500 |
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|a Date Completed 05.01.2010
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|a Date Revised 01.12.2018
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE: To investigate the effects of Ringer's solution (RS) or 6% hydroxyethyl saline (HES) on bacterial translocation and inflammation of the small intestine in rats with hemorrhagic shock
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|a METHODS: Fifty healthy male SD rats were randomly divided into the sham group (SHA group, n=10), the Ringer's solution group (RS group, n=20) and 6% hydroxyethyl saline group (HES group, n=20). Controlled hemorrhagic shock model was reproduced in RS and HES groups. Bacterial translocation to the liver, the content of tumor necrosis factor-alpha (TNF-alpha) in intestinal tissue, and the myeloperoxidase (MPO) activity in the intestinal tissue were determined and compared among the groups, and the pathologic changes in the small intestine were observed
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|a RESULTS: The mortality rate, bleeding volume and Chiu's scores were same in HES and RS groups (all P>0.05). Compared to SHA group, bacterial count and TNF-alpha level were increased significantly in HES and RS groups, and they were higher at 1 hour and lower at 24 hours in HES group than those in RS group. Compared to the SHA group, MPO activity increased at 1 hour in RS and HES groups, but no significant difference between the groups was found at 24 hours
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|a CONCLUSION: RS prevents compromise of the intestinal barrier function better than the HES at 1 hour after fluid resuscitation. However, HES seems to be better in protecting the intestinal barrier function compared with RS at 24 hours after fluid resuscitation
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|a Comparative Study
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Hydroxyethyl Starch Derivatives
|2 NLM
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|a Isotonic Solutions
|2 NLM
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|a Tumor Necrosis Factor-alpha
|2 NLM
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7 |
|a Ringer's Solution
|2 NLM
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|a 8026-10-6
|2 NLM
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|a Peroxidase
|2 NLM
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7 |
|a EC 1.11.1.7
|2 NLM
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1 |
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|a Zhou, Qiang
|e verfasserin
|4 aut
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700 |
1 |
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|a Wu, Chang-yi
|e verfasserin
|4 aut
|
700 |
1 |
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|a Pang, Qing-feng
|e verfasserin
|4 aut
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700 |
1 |
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|a Cao, Jun-li
|e verfasserin
|4 aut
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700 |
1 |
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|a Zeng, Yin-ming
|e verfasserin
|4 aut
|
773 |
0 |
8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 18(2006), 3 vom: 09. März, Seite 146-9
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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773 |
1 |
8 |
|g volume:18
|g year:2006
|g number:3
|g day:09
|g month:03
|g pages:146-9
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|a GBV_USEFLAG_A
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|a SYSFLAG_A
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|a GBV_NLM
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912 |
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|a GBV_ILN_350
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951 |
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|a AR
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952 |
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|d 18
|j 2006
|e 3
|b 09
|c 03
|h 146-9
|