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231223s2006 xx ||||| 00| ||chi c |
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|a pubmed25n0537.xml
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|a (DE-627)NLM161042376
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|a (NLM)16512643
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a chi
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| 100 |
1 |
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|a Li, Zhi-jun
|e verfasserin
|4 aut
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1 |
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|a Experimental study of protective effects of Xuebijing injection on stress-induced organ damage in rabbit
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|c 2006
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 05.01.2010
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE: To investigate the protective effects of the integrated traditional Chinese and western medicine Xuebijing injection on stress-induced organ damage in rabbits
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|a METHODS: Forty rabbits were randomly divided into four groups: the control group, the model group, the western medicine group, and the Xuebijing group. The stress-induced organ damage model was replicated by soak the rabbits in water, the animals in the western medicine group and Xuebijing group received injection of lytic cocktail and Xuebijing, respectively. The changes in cortisol (Cor), thromboxane A(2) (TXA(2)), endothelin (ET), nitric oxide synthase (NOS) were determined at different time points in all the groups. The pathologic changes of the gastric mucosa, the adrenal gland and the cardiac muscle cell were observed
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|a RESULTS: The content of Cor increased significantly in model group (P<0.01). The content of Cor decreased in the western medicine group and Xuebijing group, the changes showed no significant difference between two groups (P>0.05). The contents of ET, TXA(2) decreased and NOS increased in Xuebijing group compared with the western medicine group, the differences were significant (all P<0.05). The pathological changes of the gastric mucosa, the adrenal gland and the cardiac myocyte were less marked in Xuebijing group, compared with the western medicine group, the difference was significant (P<0.05)
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|a CONCLUSION: Xuebijing has better protective effects on stress-induced organ damage
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|a Comparative Study
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|a English Abstract
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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| 650 |
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|a Drugs, Chinese Herbal
|2 NLM
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| 650 |
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|a Endothelins
|2 NLM
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| 650 |
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|a Thromboxane A2
|2 NLM
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| 650 |
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|a 57576-52-0
|2 NLM
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| 650 |
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|a Nitric Oxide Synthase
|2 NLM
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| 650 |
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|a EC 1.14.13.39
|2 NLM
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| 650 |
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|a Hydrocortisone
|2 NLM
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| 650 |
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|a WI4X0X7BPJ
|2 NLM
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| 700 |
1 |
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|a Sun, Yuan-ying
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wu, Yun-liang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Yin-ping
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Wan-xiang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Hong-shuan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Chin-ta
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 18(2006), 2 vom: 10. Feb., Seite 105-8
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
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|g volume:18
|g year:2006
|g number:2
|g day:10
|g month:02
|g pages:105-8
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|a GBV_USEFLAG_A
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|a SYSFLAG_A
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|a GBV_NLM
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|a GBV_ILN_350
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|a AR
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|d 18
|j 2006
|e 2
|b 10
|c 02
|h 105-8
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