Undifferentiated tumor in the ovary of a corn snake (Elaphe guttata guttata)

A 6-year-old intact female corn snake (Elaphe guttata guttata) was presented with a 3-week history of anorexia. Coelomic radiographs revealed a 9 x 4 cm soft tissue opacity suggestive of a right ovarian enlargement. The mass (9 x 5 x 4 cm) was surgically removed, and multiple smears from tissue sect...

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Détails bibliographiques
Publié dans:Veterinary clinical pathology. - 1975. - 35(2006), 1 vom: 01. März, Seite 95-100
Auteur principal: Petterino, Claudio (Auteur)
Autres auteurs: Bedin, Marco, Podestá, Giorgia, Ratto, Alessandra
Format: Article
Langue:English
Publié: 2006
Accès à la collection:Veterinary clinical pathology
Sujets:Case Reports Journal Article
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100 1 |a Petterino, Claudio  |e verfasserin  |4 aut 
245 1 0 |a Undifferentiated tumor in the ovary of a corn snake (Elaphe guttata guttata) 
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520 |a A 6-year-old intact female corn snake (Elaphe guttata guttata) was presented with a 3-week history of anorexia. Coelomic radiographs revealed a 9 x 4 cm soft tissue opacity suggestive of a right ovarian enlargement. The mass (9 x 5 x 4 cm) was surgically removed, and multiple smears from tissue sections were stained with Diff-Quik. Multiple tissue samples from the mass were collected and fixed in formalin. Cytologic specimens were moderately cellular and contained light pink amorphous background material. The cells were primarily spindle-shaped with moderate to marked anisocytosis and anisokaryosis. Cells sometimes were round to polygonal, and rarely were arranged in small clusters. Macrophages occasionally were observed. Histologic specimens consisted of a highly cellular mass composed of pleomorphic, spindle-shaped cells and, occasionally, round to polygonal cells arranged in irregular fascicles. The neoplastic cells were immunoreactive for cytokeratin (AE1/AE3), smooth muscle actin, and skeletal muscle actin, but did not stain for vimentin or desmin. On the basis of the morphologic and immunohistochemical results, a diagnosis of ovarian undifferentiated carcinoma was made. In this report, we describe the challenges of using immunohistochemistry to diagnose this uncommon type of tumor in reptiles 
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700 1 |a Bedin, Marco  |e verfasserin  |4 aut 
700 1 |a Podestá, Giorgia  |e verfasserin  |4 aut 
700 1 |a Ratto, Alessandra  |e verfasserin  |4 aut 
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