Use of Oil Red O stain in the cytologic diagnosis of canine liposarcoma

BACKGROUND: Oil Red O, a stain commonly used to demonstrate lipid in frozen tissue, also may be used to stain air-dried cytologic specimens

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 35(2006), 1 vom: 01. März, Seite 37-41
1. Verfasser: Masserdotti, Carlo (VerfasserIn)
Weitere Verfasser: Bonfanti, Ugo, De Lorenzi, Davide, Ottolini, Nicola
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Journal Article Azo Compounds Coloring Agents oil red O G7S71FND9B
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245 1 0 |a Use of Oil Red O stain in the cytologic diagnosis of canine liposarcoma 
264 1 |c 2006 
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500 |a Date Completed 05.05.2006 
500 |a Date Revised 09.11.2019 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a BACKGROUND: Oil Red O, a stain commonly used to demonstrate lipid in frozen tissue, also may be used to stain air-dried cytologic specimens 
520 |a OBJECTIVE: The purpose of this study was to prospectively evaluate the value of Oil Red O in identifying lipid to aid in the differentiation of liposarcomas from other types of sarcoma 
520 |a METHODS: Twelve tumor specimens from dogs were evaluated. The tumors were included in the study if initial cytologic evaluation indicated a sarcoma, and if histologic confirmation was available. Oil Red O was applied to all cytologic specimens 
520 |a RESULTS: Tumor specimens were diagnosed histologically as liposarcoma (3 well-differentiated, 1 pleomorphic), hemangiopericytoma (n = 3), fibrosarcoma (n = 3), malignant fibrous histiocytoma (n = 1), and undifferentiated sarcoma (n = 1). Cytologic specimens from all liposarcomas showed strong positive staining of cytoplasmic vacuoles for lipid. Specimens from other sarcomas stained negative for Oil Red O, with the exception of weak, irregular positive staining in 1 hemangiopericytoma 
520 |a CONCLUSION: Our results suggest that Oil Red O staining may be an easy, inexpensive, and useful diagnostic tool for the differentiation of liposarcoma from other mesenchymal neoplasms 
650 4 |a Journal Article 
650 7 |a Azo Compounds  |2 NLM 
650 7 |a Coloring Agents  |2 NLM 
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700 1 |a De Lorenzi, Davide  |e verfasserin  |4 aut 
700 1 |a Ottolini, Nicola  |e verfasserin  |4 aut 
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