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231223s2006 xx ||||| 00| ||eng c |
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|a pubmed25n0537.xml
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|a (DE-627)NLM161022030
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|a (NLM)16510519
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Scott, Iain
|e verfasserin
|4 aut
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| 245 |
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|a BIGYIN, an orthologue of human and yeast FIS1 genes functions in the control of mitochondrial size and number in Arabidopsis thaliana
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|c 2006
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 03.08.2006
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|a Date Revised 30.09.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Reverse-genetics was used to evaluate the role of an Arabidopsis homologue of the human and yeast FIS1 genes, which are both involved in mitochondrial fission. Two independent T-DNA insertion mutants of gene At3g57090 were identified and genetically transformed to express mitochondria-targeted GFP to enable visualization of mitochondria in vivo. Plants homozygous for either of the recessive T-DNA mutant alleles, termed bigyin1-1 (bgy1-1) and bigyin1-2 (bgy1-2), displayed an abnormal mitochondrial morphology. Disruption of BIGYIN leads to a reduced number of mitochondria per cell, coupled to a large increase in the size of individual mitochondria, relative to wild-type. It is concluded that BIGYIN is an Arabidopsis FIS orthologue and is part of the Arabidopsis mitochondrial division apparatus
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Arabidopsis Proteins
|2 NLM
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| 650 |
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|a BIGYIN protein, Arabidopsis
|2 NLM
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| 650 |
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|a FIS1 protein, S cerevisiae
|2 NLM
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| 650 |
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|a FIS1 protein, human
|2 NLM
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| 650 |
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|a Membrane Proteins
|2 NLM
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| 650 |
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|a Mitochondrial Proteins
|2 NLM
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| 650 |
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|a Mutant Proteins
|2 NLM
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| 650 |
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|a Saccharomyces cerevisiae Proteins
|2 NLM
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| 700 |
1 |
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|a Tobin, Alyson K
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Logan, David C
|e verfasserin
|4 aut
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| 773 |
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8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 57(2006), 6 vom: 15., Seite 1275-80
|w (DE-627)NLM098182706
|x 0022-0957
|7 nnns
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| 773 |
1 |
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|g volume:57
|g year:2006
|g number:6
|g day:15
|g pages:1275-80
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|d 57
|j 2006
|e 6
|b 15
|h 1275-80
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