Amelioration of murine lupus by a peptide, based on the complementarity determining region-1 of an autoantibody as compared to dexamethasone different effects on cytokines and apoptosis

Amelioration of murine lupus by a peptide, based on the complementarity determining region-1 of an autoantibody as compared to dexamethasone : different effects on cytokines and apoptosis

A peptide (hCDR1) based on the sequence of the complementarity-determining region-1 of an anti-DNA autoantibody ameliorates clinical manifestations of lupus. We analyzed the beneficial effects of hCDR1 when given alone or in combination with dexamethasone, while comparing the mechanisms of action of...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 2 vom: 18. Mai, Seite 146-55
1. Verfasser: Sharabi, Amir (VerfasserIn)
Weitere Verfasser: Haviv, Asher, Zinger, Heidy, Dayan, Molly, Mozes, Edna
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Comparative Study Journal Article Anti-Inflammatory Agents Autoantibodies Complementarity Determining Regions Cytokines FASLG protein, human Fas Ligand Protein Fasl protein, mouse Membrane Glycoproteins mehr... Peptide Fragments Tumor Necrosis Factors Dexamethasone 7S5I7G3JQL