A chimeric human-cat Fcgamma-Fel d1 fusion protein inhibits systemic, pulmonary, and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1, the major cat allergen

A chimeric human-cat Fcgamma-Fel d1 fusion protein inhibits systemic, pulmonary, and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1, the major cat allergen

Co-aggregation of FcepsilonRI with FcgammaRIIb can block FcepsilonRI-mediated reactivity and Fc gamma:allergen chimeric proteins, by co-crosslinking FcgammaRIIb to allergen-specific IgE bound to the FcepsilonRI can block allergen-specific reactivity. We evaluated whether a human cat chimeric fusion...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 1 vom: 15. Juli, Seite 45-56
Auteur principal: Terada, Tetsuya (Auteur)
Autres auteurs: Zhang, Ke, Belperio, John, Londhe, Vedang, Saxon, Andrew
Format: Article
Langue:English
Publié: 2006
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article FCGR1A protein, human Glycoproteins Immunoglobulin G Receptors, IgG Recombinant Fusion Proteins Immunoglobulin E 37341-29-0 Fel d 1 protein, Felis domesticus G408EE88II