Self-assembly of beta-cyclodextrin in water. Part 1 : Cryo-TEM and dynamic and static light scattering

In this article, we report evidence of beta-cyclodextrin (beta-CD) self-aggregation in water. A critical aggregation concentration (cac) between 2 and 3 mM was determined by using dynamic (DLS) and static (SLS) light scattering to investigate the presence of beta-cyclodextrin aggregates. Transmissio...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 22(2006), 4 vom: 14. Feb., Seite 1478-84
1. Verfasser: Bonini, Massimo (VerfasserIn)
Weitere Verfasser: Rossi, Simona, Karlsson, Göran, Almgren, Mats, Lo Nostro, Pierandrea, Baglioni, Piero
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't beta-Cyclodextrins Water 059QF0KO0R betadex JV039JZZ3A
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520 |a In this article, we report evidence of beta-cyclodextrin (beta-CD) self-aggregation in water. A critical aggregation concentration (cac) between 2 and 3 mM was determined by using dynamic (DLS) and static (SLS) light scattering to investigate the presence of beta-cyclodextrin aggregates. Transmission electron microscopy at cryogenic temperature (Cryo-TEM) was used to detect the structural features of cyclodextrin self-aggregates. The results show the occurrence of polymorphism depending on the beta-CD concentration: polydisperse nearly spherical objects with diameters of about 100 nm are present at lower concentrations, whereas micrometer planar aggregates are predominant at higher concentrations 
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700 1 |a Rossi, Simona  |e verfasserin  |4 aut 
700 1 |a Karlsson, Göran  |e verfasserin  |4 aut 
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700 1 |a Lo Nostro, Pierandrea  |e verfasserin  |4 aut 
700 1 |a Baglioni, Piero  |e verfasserin  |4 aut 
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