Biological activities on T lymphocytes of a baculovirus-expressed chimeric recombinant IgG1 antibody with specificity for the CDR3-like loop on the D1 domain of the CD4 molecule

Biological activities on T lymphocytes of a baculovirus-expressed chimeric recombinant IgG1 antibody with specificity for the CDR3-like loop on the D1 domain of the CD4 molecule

A baculovirus-expressed chimeric recombinant IgG1 (rIgG1) antibody, with Cgamma1 and Ckappa human constant domains, was derived from the murine monoclonal antibody (mAb) 13B8.2, which is specific for the CDR3-like loop of the CD4 molecule and which inhibits HIV-1 replication. Chimeric rIgG1 antibody...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 1 vom: 28. Apr., Seite 38-50
1. Verfasser: Troadec, Samuel (VerfasserIn)
Weitere Verfasser: Bès, Cédric, Chentouf, Myriam, Nguyen, Brigitte, Briant, Laurence, Jacquet, Chantal, Chebli, Karim, Pugnière, Martine, Roquet, Françoise, Cerutti, Martine, Chardès, Thierry
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal CD3 Complex CD4 Antigens Epitopes Immunoglobulin G Interleukin-2 Recombinant Fusion Proteins Ionomycin mehr... 56092-81-0 Tetradecanoylphorbol Acetate NI40JAQ945