CD8+HLA-DR+ T lymphocytes are increased in common variable immunodeficiency patients with impaired memory B-cell differentiation

CD8+HLA-DR+ T lymphocytes are increased in common variable immunodeficiency patients with impaired memory B-cell differentiation

The recently proposed Piqueras classification of common variable immunodeficiency (CVID) patients is based on flow cytometric quantification of IgD class-switched and CD27 membrane-expressing mature blood B cells. But, many patients also have circulating T cells with immunophenotypic abnormalities,...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 1 vom: 28. Apr., Seite 51-8
1. Verfasser: Viallard, Jean-François (VerfasserIn)
Weitere Verfasser: Blanco, Patrick, André, Marc, Etienne, Gabriel, Liferman, François, Neau, Didier, Vidal, Elisabeth, Moreau, Jean-François, Pellegrin, Jean-Luc
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Antigens, CD19 CCR7 protein, human HLA-DR Antigens Membrane Glycoproteins Pore Forming Cytotoxic Proteins Receptors, CCR7 Receptors, Chemokine Perforin 126465-35-8 mehr... Leukocyte Common Antigens EC 3.1.3.48 GZMB protein, human EC 3.4.21.- Granzymes Serine Endopeptidases