Ex vivo expansion of dendritic-cell-activated antigen-specific CD4+ T cells with anti-CD3/CD28, interleukin-7, and interleukin-15 potential for adoptive T cell immunotherapy

Ex vivo expansion of dendritic-cell-activated antigen-specific CD4+ T cells with anti-CD3/CD28, interleukin-7, and interleukin-15 : potential for adoptive T cell immunotherapy

There is an increasing realization that the failure of adoptive therapy with cytotoxic T lymphocytes in the autologous setting, at least in part, results from the lack of help from antigen-specific CD4+ T cells. To incorporate these cells into this treatment strategy, it is not known whether current...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 1 vom: 01. Apr., Seite 21-31
1. Verfasser: Chen, Hao-Wei (VerfasserIn)
Weitere Verfasser: Liao, Cheng-Hao, Ying, Chingwen, Chang, Chun-Jung, Lin, Chun-Ming
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Antibodies Antigens, CD CD28 Antigens CD3 Complex Hepatitis B Surface Antigens Interleukin-15 Interleukin-2 Interleukin-7 Interleukins mehr... KLRK1 protein, human NK Cell Lectin-Like Receptor Subfamily K Receptors, Immunologic Receptors, Interleukin-2 Receptors, Natural Killer Cell Receptors, Nerve Growth Factor Receptors, Tumor Necrosis Factor TNFRSF9 protein, human Transforming Growth Factor beta Tumor Necrosis Factor Receptor Superfamily, Member 9 Interferon-gamma 82115-62-6