CD4+ T cell receptor repertoire perturbations in HIV-1 infection : association with plasma viremia and disease progression

CD4+ T cell depletion and dysfunction are the hallmark of HIV-1 disease. Our primary objectives were to define the diversity of the CD4+ T cell receptor Vbeta (TCRBV) repertoire in subjects with HIV-1 infection by CDR3 (complementarity-determining region) length spectratyping and to determine the co...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 1 vom: 30. Apr., Seite 95-102
1. Verfasser:	Malhotra, Uma (VerfasserIn)
Weitere Verfasser:	Huntsberry, Claire, Holte, Sarah, Lee, Jean, Corey, Lawrence, McElrath, M Juliana
Format:	Aufsatz
Sprache:	English
Veröffentlicht:	2006
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Anti-Retroviral Agents Complementarity Determining Regions RNA, Viral Receptors, Antigen, T-Cell, alpha-beta