Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors
The inhibitors of HMG CoA reductase (statins) are widely used as cholesterol-lowering drugs with excellent safety records in hypercholesterolemic patients. Statins exert pleiotropic effects on a variety of cells, and they were recently described as a new class of immune modulators. Depending on thei...
Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 1 vom: 15. Apr., Seite 1-12 |
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Auteur principal: | |
Autres auteurs: | , |
Format: | Article |
Langue: | English |
Publié: |
2006
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Accès à la collection: | Clinical immunology (Orlando, Fla.) |
Sujets: | Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Heptanoic Acids Hydroxymethylglutaryl-CoA Reductase Inhibitors Pyrroles Cholesterol 97C5T2UQ7J Atorvastatin |