Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors

The inhibitors of HMG CoA reductase (statins) are widely used as cholesterol-lowering drugs with excellent safety records in hypercholesterolemic patients. Statins exert pleiotropic effects on a variety of cells, and they were recently described as a new class of immune modulators. Depending on thei...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 1 vom: 15. Apr., Seite 1-12
Auteur principal: Brumeanu, Teodor-D (Auteur)
Autres auteurs: Goldstein, Robert, Casares, Sofia
Format: Article
Langue:English
Publié: 2006
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Heptanoic Acids Hydroxymethylglutaryl-CoA Reductase Inhibitors Pyrroles Cholesterol 97C5T2UQ7J Atorvastatin A0JWA85V8F