Changes of myocardial dynamics in early stage of burn and effect of rapid fluid replacement in delayed resuscitation

OBJECTIVE: To investigate the changes in myocardial dynamics in early phases of burn shock of dogs and the effects of rapid fluid infusion in delayed resuscitation

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 17(2005), 12 vom: 16. Dez., Seite 756-8
1. Verfasser: Wang, De-wei (VerfasserIn)
Weitere Verfasser: Wang, Chang-hui, Ding, Xiang-sheng, Pei, Yong-dong, Zhu, Shi-hui, Liu, Shi-kang, Ge, Sheng-de
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Isotonic Solutions Ringer's Lactate
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245 1 0 |a Changes of myocardial dynamics in early stage of burn and effect of rapid fluid replacement in delayed resuscitation 
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500 |a Date Revised 03.12.2018 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To investigate the changes in myocardial dynamics in early phases of burn shock of dogs and the effects of rapid fluid infusion in delayed resuscitation 
520 |a METHODS: Twelve mongrel dogs were randomly divided into control (n=6) and burn (n=6) groups. The dogs in burn group were subjected to 35% total body surface area (TBSA) III degree burn and were resuscitated with lactate Ringer's solution 6 hours postburn. The volumes and rates of fluid infusion were controlled basically on the urinary output of 1.0 mlxkg(-1)xh(-1) and cardiac output (CO) of 70%-80% of pre-burn values. The mean arterial pressure (MAP), left ventricular systolic pressure (LVSP), maximum rate of intraventricular pressure rise/down (+/-dp/dt max) and cardiac index (CI) were determined at 0.5, 1,2, 6, 7, 8, 10 and 24 hours postburn 
520 |a RESULTS: The MAP, LVSP, +/-dp/dt max and CI were significantly lowered from their baseline and those of control group at 0.5 hour postburn, and they kept declining until 6 hours postburn. They showed a tendency of elevation and reached or approached the levels of that in control group within 2 hours of resuscitation, and the differences were not significant between the two groups 4 hours after burn (all P>0.05). The amount of infusion fluid within the first 4 hours of resuscitation was (3.63+/-0.99) ml/kg per 1% TBSA 
520 |a CONCLUSION: The myocardial dynamics is depressed in the early stage of burn, the effective way to improve it is to infuse a large amount of fluid rapidly when resuscitation is delayed 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Isotonic Solutions  |2 NLM 
650 7 |a Ringer's Lactate  |2 NLM 
700 1 |a Wang, Chang-hui  |e verfasserin  |4 aut 
700 1 |a Ding, Xiang-sheng  |e verfasserin  |4 aut 
700 1 |a Pei, Yong-dong  |e verfasserin  |4 aut 
700 1 |a Zhu, Shi-hui  |e verfasserin  |4 aut 
700 1 |a Liu, Shi-kang  |e verfasserin  |4 aut 
700 1 |a Ge, Sheng-de  |e verfasserin  |4 aut 
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