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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Kang, Taewook
|e verfasserin
|4 aut
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| 245 |
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|a Characterization of surface-confined alpha-synuclein by surface plasmon resonance measurements
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|c 2006
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|b nc
|2 rdacarrier
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|a Date Completed 18.04.2007
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a Urea-driven denaturation and renaturation of surface-bound alpha-synuclein are monitored by surface plasmon resonance (SPR) spectroscopy. The differential SPR angle shift (Delta Theta(SPR))(Net) enables us to estimate the Gibbs free energy change (DeltaG(o)) for the denaturation of the supported alpha-synuclein. DeltaG(o) for the denaturation of the supported alpha-synuclein, which is indirectly related to its biological activity can be increased significantly by the mixed self-assembled monolayers of 11-mercaptoundecanoic acid and 1,6-hexanedithiol. These SPR measurements of surface-bound biomolecules suggested herein can be further utilized to design effective biological scaffold for biosensor, biocatalyst, and possible diagnosis
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Coated Materials, Biocompatible
|2 NLM
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|a Recombinant Proteins
|2 NLM
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|a alpha-Synuclein
|2 NLM
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|a Urea
|2 NLM
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|a 8W8T17847W
|2 NLM
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| 700 |
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|a Hong, Surin
|e verfasserin
|4 aut
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|a Kim, Hyun Jin
|e verfasserin
|4 aut
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|a Moon, Jungwoo
|e verfasserin
|4 aut
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| 700 |
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|a Oh, Seogil
|e verfasserin
|4 aut
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|a Paik, Seung R
|e verfasserin
|4 aut
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|a Yi, Jongheop
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 22(2006), 1 vom: 03. Jan., Seite 13-7
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:22
|g year:2006
|g number:1
|g day:03
|g month:01
|g pages:13-7
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