Altered collagen II peptides inhibited T-cell activation in rheumatoid arthritis
It has been reported that collagen II (CII)-derived peptide induced T-cell activation via its amino acids responsible for T-cell receptor (TCR) recognition. In this study, three altered CII263-272 peptide ligands (APL) containing multiple substitutions of TCR contact residues were synthesized. Their...
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 118(2006), 2-3 vom: 15. Feb., Seite 317-23 |
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Format: | Aufsatz |
Sprache: | English |
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2006
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Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Antigens, CD Antigens, Differentiation, T-Lymphocyte CD69 antigen Collagen Type II Cytokines HLA-DR4 Antigen Immunosuppressive Agents Lectins, C-Type mehr... |