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|a DE-627
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Awad, Tarek S
|e verfasserin
|4 aut
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| 245 |
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|a Formation of cubic phases from large unilamellar vesicles of dioleoylphosphatidylglycerol/monoolein membranes induced by low concentrations of Ca2+
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|c 2005
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 21.05.2015
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| 500 |
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|a Date Revised 30.11.2005
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|a published: Print
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|a Citation Status PubMed-not-MEDLINE
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|a We developed a new method for the transformation of large unilamellar vesicles (LUVs) into the cubic phase. We found that the addition of low concentrations of Ca(2+) to suspensions of multilamellar vesicles (MLVs) of membranes of monoolein (MO) and dioleoylphosphatidylglycerol (DOPG) mixtures (DOPG/MO) changed their L(alpha) phase to the cubic phases. For instance, the addition of 15-25 mM Ca(2+) to 30%-DOPG/70%-MO-MLVs induced the Q(229) phase, whereas the addition of > or =28 mM Ca(2+) induced the Q(224) phase. LUVs of DOPG/MO membranes containing > or =25 mol % DOPG were prepared easily. Low concentrations of Ca(2+) transformed these LUVs in excess buffer into the Q(224) or the Q(229) phase, depending on the Ca(2+) concentration. For example, 15 and 50 mM Ca(2+) induced the Q(224) and Q(229) phase in the 30%-DOPG/70%-MO-LUVs at 25 degrees C, respectively. This finding is the first demonstration of transformation of LUVs of lipid membranes into the cubic phase under excess water condition
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| 650 |
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|a Journal Article
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| 700 |
1 |
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|a Okamoto, Yoshihide
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Masum, Shah Md
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yamazaki, Masahito
|e verfasserin
|4 aut
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| 773 |
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8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 21(2005), 25 vom: 06. Dez., Seite 11556-61
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:21
|g year:2005
|g number:25
|g day:06
|g month:12
|g pages:11556-61
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|d 21
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|h 11556-61
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