Inflammatory modulation of PPAR gamma expression and activity

Inflammatory modulation of PPAR gamma expression and activity

Nitric oxide (NO) production increases with age in the lupus-prone MRL/lpr mouse, paralleling disease activity. One mechanism for excess NO production in MRL/lpr mice may be a defect in down-regulatory mechanisms of the iNOS pathway. A potential modulator of NO is the nuclear hormone receptor peroxi...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 118(2006), 2-3 vom: 15. Feb., Seite 276-83
1. Verfasser: Crosby, Michelle B (VerfasserIn)
Weitere Verfasser: Zhang, John, Nowling, Tamara M, Svenson, John L, Nicol, Christopher J, Gonzalez, Frank J, Gilkeson, Gary S
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Inflammation Mediators PPAR gamma Nitric Oxide 31C4KY9ESH Nitric Oxide Synthase Type II EC 1.14.13.39 Nos2 protein, mouse