Synthesis of monodisperse biodegradable microgels in microfluidic devices
Microgels are promising materials in drug delivery and biomedicine. Although monodisperse microgels would offer considerable advantages, most microgels investigated and used today are polydisperse in size. We report on the fabrication of 10 mum sized monodisperse microgels by emulsifying an aqueous...
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1991. - 21(2005), 23 vom: 08. Nov., Seite 10275-9 |
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1. Verfasser: | |
Weitere Verfasser: | , , , |
Format: | Aufsatz |
Sprache: | English |
Veröffentlicht: |
2005
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Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
Schlagworte: | Letter Research Support, Non-U.S. Gov't Biocompatible Materials Gels Methacrylates hydroxyethyl methacrylate 6E1I4IV47V |
Zusammenfassung: | Microgels are promising materials in drug delivery and biomedicine. Although monodisperse microgels would offer considerable advantages, most microgels investigated and used today are polydisperse in size. We report on the fabrication of 10 mum sized monodisperse microgels by emulsifying an aqueous dextran-hydroxyethyl methacrylate (dex-HEMA) phase within an oil phase at the junction of microfluidic channels. Dex-HEMA microgels are biodegradable and are ideally suited for the controlled delivery of proteins |
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Beschreibung: | Date Completed 04.05.2007 Date Revised 15.11.2012 published: Print Citation Status MEDLINE |
ISSN: | 0743-7463 |