HLA B44 is associated with decreased severity of autoimmune lymphoproliferative syndrome in patients with CD95 defects (ALPS type Ia)

HLA B44 is associated with decreased severity of autoimmune lymphoproliferative syndrome in patients with CD95 defects (ALPS type Ia)

Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte apoptosis characterized by non-malignant lymphadenopathy and splenomegaly, expansion of T cells without either CD4 or CD8 surface markers, and increased incidence of autoimmune diseases and lymphoma. Most patients with ALPS h...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 118(2006), 1 vom: 15. Jan., Seite 59-65
1. Verfasser: Vacek, Marla M (VerfasserIn)
Weitere Verfasser: Schäffer, Alejandro A, Davis, Joie, Fischer, Roxanne E, Dale, Janet K, Adams, Sharon, Straus, Stephen E, Puck, Jennifer M
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Intramural FAS protein, human HLA-B Antigens HLA-B44 Antigen HLA-DQ Antigens HLA-DQ beta-Chains HLA-DQB1 antigen HLA-Dx antigen Receptors, Tumor Necrosis Factor fas Receptor