Molecular epidemiology of human caliciviruses diarrhea among infants and young children in Lanzhou from December 2001 to June 2004

OBJECTIVE: To investigate the characteristics of human caliciviruses (HuCV) diarrhea among infants and young children with acute diarrhea in Lanzhou, Gansu Province, China by using molecular epidemiologic techniques

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 43(2005), 9 vom: 29. Sept., Seite 657-60
1. Verfasser: Jin, Yu (VerfasserIn)
Weitere Verfasser: Huang, Xiang, Fang, Zhao-yin, Tan, Jia-yu, Dong, Qiao-li, Xie, Hua-ping, Zhang, Jing
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't RNA, Viral
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245 1 0 |a Molecular epidemiology of human caliciviruses diarrhea among infants and young children in Lanzhou from December 2001 to June 2004 
264 1 |c 2005 
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500 |a Date Revised 07.06.2016 
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500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To investigate the characteristics of human caliciviruses (HuCV) diarrhea among infants and young children with acute diarrhea in Lanzhou, Gansu Province, China by using molecular epidemiologic techniques 
520 |a METHODS: Stool specimens were collected from both outpatients and inpatients with acute diarrhea in Lanzhou. Enzyme-linked immunosorbant assay (ELISA) was used to detect rotavirus antigen (RVA). Reverse transcription-polymerase chain reactions (RT-PCR) were used to detect HuCV in stool specimens of RV ELISA (-) 
520 |a RESULTS: Of the stool specimens collected from 515 cases in Lanzhou from December 2001 to June 2004, 264 were RVA ELISA (+) and 251 were RVA ELISA (-). Among all cases who were RVA ELISA (-), 25 (9.96%) were found positive for HuCV. HuCV was detected in 12 of 133 cases (9.02%) from December 2001 to November 2002, no genotyping was performed for these cases. From July 2003 to June 2004 13 of 118 cases (11.02%) were found positive for HuCV, of whom 11 cases had Norwalk-like virus GII (NLV GII) infection and 2 cases had Sapporo-like virus infection (one case had combined infection with astrovirus) and no NLV GI was found. HuCV infection mainly occurred in children under 2 years of age and no seasonal cluster was found 
520 |a CONCLUSION: HuCV is one of the major etiological agents of viral diarrhea among infants and young children in Lanzhou. NLV GII maybe the predominant genotype 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
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700 1 |a Huang, Xiang  |e verfasserin  |4 aut 
700 1 |a Fang, Zhao-yin  |e verfasserin  |4 aut 
700 1 |a Tan, Jia-yu  |e verfasserin  |4 aut 
700 1 |a Dong, Qiao-li  |e verfasserin  |4 aut 
700 1 |a Xie, Hua-ping  |e verfasserin  |4 aut 
700 1 |a Zhang, Jing  |e verfasserin  |4 aut 
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