The therapeutic potential of anti-CD20 "what do B-cells do?"

B-cells play a major role in the immunopathogenesis of autoimmune diseases. Not only do they produce autoantibodies, but they regulate other cell types, secrete cytokines, and present antigens. They are thus potential targets for therapeutic intervention. CD20 is a B-cell specific cell surface molec...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 117(2005), 3 vom: 15. Dez., Seite 207-13
1. Verfasser: Eisenberg, Robert (VerfasserIn)
Weitere Verfasser: Looney, R John
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Review Antibodies, Monoclonal Antibodies, Monoclonal, Murine-Derived Antigens, CD20 Immunologic Factors Rituximab 4F4X42SYQ6