Apoptosis of neutrophil in peripheral blood in experimental sepsis

OBJECTIVE: To evaluate the changes in apoptosis of neutrophil in peripheral blood in sepsis in rats

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 17(2005), 9 vom: 08. Sept., Seite 561-4
1. Verfasser: Xi, Jian-cheng (VerfasserIn)
Weitere Verfasser: Zhou, Bao-tong, Jiang, Li-xian, Jiang, Xiao-guo, Sun, Tong-zhu, Yang, Yi
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't
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245 1 0 |a Apoptosis of neutrophil in peripheral blood in experimental sepsis 
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500 |a Date Completed 07.08.2009 
500 |a Date Revised 08.09.2005 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To evaluate the changes in apoptosis of neutrophil in peripheral blood in sepsis in rats 
520 |a METHODS: The rat sepsis model was reproduced by cecum ligation and puncture (CLP). One hundred and forty-four rats were randomly divided into normal control group, sham operation group and 2, 6, 12, 24, 48, 72 hours after CLP groups. Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) was used to identify neutrophil apoptosis 
520 |a RESULTS: In early period after CLP, neutrophil apoptosis in peripheral blood was limited with a positive rate of less than 5.00%. The positive rate rose to (48.33+/-12.53)% at 48 hours, and it began to lower, approaching the normal level at 72 hours after CLP 
520 |a CONCLUSION: Death is the main pathway of loss of neutrophils which are produced in the acute phase of sepsis, and apoptosis is the main pathway of loss of neutrophil in the later phase of sepsis 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Zhou, Bao-tong  |e verfasserin  |4 aut 
700 1 |a Jiang, Li-xian  |e verfasserin  |4 aut 
700 1 |a Jiang, Xiao-guo  |e verfasserin  |4 aut 
700 1 |a Sun, Tong-zhu  |e verfasserin  |4 aut 
700 1 |a Yang, Yi  |e verfasserin  |4 aut 
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