Detergent binding as a sensor of hydrophobicity and polar interactions in the binding cavities of proteins

Detergent binding as a sensor of hydrophobicity and polar interactions in the binding cavities of proteins

To evaluate the role of hydrophobic and electrostatic or other polar interactions for protein-ligand binding, we studied the interaction of human serum albumin (HSA) and beta-lactoglobulin with various aliphatic (C10-C14) cationic and zwitterionic detergents. We find that cationic detergents, at lev...

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Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 21(2005), 19 vom: 13. Sept., Seite 8865-75
Auteur principal: Peyre, Véronique (Auteur)
Autres auteurs: Lair, Virginie, André, Virginie, le Maire, Guerric, Kragh-Hansen, Ulrich, le Maire, Marc, Møller, Jesper V
Format: Article
Langue:English
Publié: 2005
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Cations Detergents Lactoglobulins Ligands Micelles Serum Albumin