NMR spectroscopic characterization of the membrane affinity of polyols
Copyright (c) 2005 John Wiley & Sons, Ltd.
| Veröffentlicht in: | Magnetic resonance in chemistry : MRC. - 1985. - 43(2005), 11 vom: 19. Nov., Seite 893-901 |
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| Format: | Aufsatz |
| Sprache: | English |
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2005
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| Zugriff auf das übergeordnete Werk: | Magnetic resonance in chemistry : MRC |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Carbon Isotopes Ligands Lipid Bilayers Polymers Protons polyol Phosphorylcholine 107-73-3 |
| Zusammenfassung: | Copyright (c) 2005 John Wiley & Sons, Ltd. Residual dipolar couplings (RDCs) are applied here for the analysis of weak, transient binding events between phosphatidylcholine bilayers and polyols. Large signal responses are observed even for low percentages of 'ligand-receptor complexes', making RDCs a sensitive tool for the analysis of molecular recognition events. The different degree of alignment in solution can be compared as a result of the calculation of the alignment tensor elements. By varying polarity and/or charge of the molecules under investigation, nonspecific hydrophobic effects can be excluded |
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| Beschreibung: | Date Completed 16.02.2006 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
| ISSN: | 1097-458X |