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231223s2005 xx ||||| 00| ||eng c |
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|a pubmed25n0525.xml
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|a (DE-627)NLM157513718
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|a (NLM)16134072
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Mylonakis, Mathios E
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Cytologic patterns of lymphadenopathy in dogs infected with Leishmania infantum
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| 264 |
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1 |
|c 2005
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 28.03.2006
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|a Date Revised 09.11.2019
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a BACKGROUND: Lymphadenopathy in canine leishmaniosis has been reported as reactive lymphoid hyperplasia or granulomatous (histiocytic) lymphadenitis. However, we are unaware of information on the effect of latent Leishmania infection on lymph node cytology compared with clinically affected dogs
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|a OBJECTIVES: The aim of the present study was to investigate cytologic patterns of lymphadenopathy in dogs with clinical and subclinical forms of leishmaniosis and to correlate cytologic findings with the density of Leishmania amastigotes in fine needle aspiration (FNA) smears
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|a METHODS: FNA cytology of prescapular or popliteal lymph nodes was evaluated on 32 dogs with clinical evidence of leishmaniosis (group A), 24 subclinically infected dogs (group B), and 17 clinically healthy noninfected dogs (group C); groups were based on the results of serologic and PCR tests for Leishmania sp. Differential nucleated cell counts (based on 300 cells) and amastigote density were determined microscopically. Cytologic findings were categorized and compared among groups
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|a RESULTS: Cytologic abnormalities were found in 19 of 32 (59.4%) dogs in group A, 1 of 24 (4.2%) dogs in group B, and 2 of 17 (11.8%) dogs in group C and were significantly more frequent in group A than group B (P <.001) or C (P = .001). In group A, 68.7% of the dogs had lymphoid hyperplasia, 12.5% had lymphoid hyperplasia and histiocytic lymphadenitis, 6.3% had histiocytic lymphadenitis, and 3.1% had lymphoid hyperplasia and neutrophilic lymphadenitis. Lymphoid hyperplasia was also noted in 1 dog in group B, and lymphoid hyperplasia and eosinophilic lymphadenitis were each found in 1 dog in group C. Lymph node smears from 31 (96.9%) dogs in group A and 6 (25%) dogs in group B were positive for Leishmania amastigotes; however, no correlation was found between the density of amastigotes and cytopathologic patterns of lymphadenopathy
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| 520 |
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|a CONCLUSION: Abnormal lymph node cytology is much more common in dogs with clinical leishmaniosis than in dogs with subclinical infection, and primarily involves lymphoid hyperplasia. Despite finding no association between the density of amastigotes and type of lymphadenopathy, lymph node cytology still is a valuable diagnostic tool for diagnosing canine leishmaniosis
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| 650 |
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4 |
|a Journal Article
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| 700 |
1 |
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|a Papaioannou, Nikolaos
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Saridomichelakis, Manolis N
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Koutinas, Alexander F
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Billinis, Charalambos
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kontos, Vassilios I
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 34(2005), 3 vom: 21. Sept., Seite 243-7
|w (DE-627)NLM098159984
|x 0275-6382
|7 nnns
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| 773 |
1 |
8 |
|g volume:34
|g year:2005
|g number:3
|g day:21
|g month:09
|g pages:243-7
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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| 912 |
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|a GBV_ILN_350
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| 951 |
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|a AR
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| 952 |
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|d 34
|j 2005
|e 3
|b 21
|c 09
|h 243-7
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