Formation of polyelectrolyte multilayer architectures with embedded DMPC studied in situ by neutron reflectometry

The coupling of lipid molecules to polymer components in a planar biomimetic model membrane made of a lipid bilayer (dimyristoylphosphatidylcholine) supported by polyelectrolyte multilayers is studied. The polyelectrolyte support was prepared by layer-by-layer deposition of positively charged poly(a...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 21(2005), 18 vom: 30. Aug., Seite 8509-14
1. Verfasser: Delajon, Christophe (VerfasserIn)
Weitere Verfasser: Gutberlet, Thomas, Steitz, Roland, Möhwald, Helmuth, Krastev, Rumen
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Electrolytes Dimyristoylphosphatidylcholine U86ZGC74V5
Beschreibung
Zusammenfassung:The coupling of lipid molecules to polymer components in a planar biomimetic model membrane made of a lipid bilayer (dimyristoylphosphatidylcholine) supported by polyelectrolyte multilayers is studied. The polyelectrolyte support was prepared by layer-by-layer deposition of positively charged poly(allylamine hydrochloride) (PAH) and negatively charged poly(sodium 4-styrenesulfonate) (PSS). Two polymer sample terminations were considered: positively charged (PAH-terminated) and negatively charged (PSS-terminated). Neutron reflectometry studies showed that, whereas positively charged samples did not favor the deposition of lipid, negatively charged samples allowed the deposition of a lipid bilayer with a thickness of approximately 5 nm. In the latter case, formation of polyelectrolyte layers after the deposition of the lipid layer was also possible
Beschreibung:Date Completed 20.03.2007
Date Revised 21.11.2013
published: Print
Citation Status MEDLINE
ISSN:1520-5827