Loading and release of charged dyes using ultrathin hydrogels

The anionic dyes methyl orange (MO) and allura red (AR) were used as model drugs to assess the loading and release by layer-by-layer assembled ultrathin hydrogels prepared via the amide formation of poly(acrylic acid-co-N-isopropylacrylamide) with AAc contents of 5, 10, and 15 mol % plus poly(vinyla...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 21(2005), 17 vom: 16. Aug., Seite 7739-42
1. Verfasser: Serizawa, Takeshi (VerfasserIn)
Weitere Verfasser: Matsukuma, Daisuke, Akashi, Mitsuru
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Acrylamides Acrylates Amides Anions Azo Compounds Coloring Agents Hydrogels Membranes, Artificial mehr... N-isopropylacrylamide-acrylic acid copolymer Polymers Polyvinyls Allura Red AC Dye 25956-17-6 poly(vinylamine) 26336-38-9 methyl orange 6B4TC34456
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520 |a The anionic dyes methyl orange (MO) and allura red (AR) were used as model drugs to assess the loading and release by layer-by-layer assembled ultrathin hydrogels prepared via the amide formation of poly(acrylic acid-co-N-isopropylacrylamide) with AAc contents of 5, 10, and 15 mol % plus poly(vinylamine hydrochloride). The amount of MO loaded was potentially controlled by changing the dye concentrations, film thickness, and AAc content of the copolymers. The release of AR was controlled by the NaCl concentration and pH. We conclude that the polymeric matrices of ultrathin hydrogels have great potential for the loading and release of charged drugs 
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700 1 |a Matsukuma, Daisuke  |e verfasserin  |4 aut 
700 1 |a Akashi, Mitsuru  |e verfasserin  |4 aut 
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